The team coached by Anthony Ndawula lost 3-0 3-0 (25-18; 25-21; 25-16) to Espérance de Tunis.
21 teams are taking part in the competition whose eventual winner will book the only slot to represent Africa at the world Club Championships to be played in Brazil in May.
On Friday Nemo’s second game is against Kenyan 2013 champions GSU.
DAY ONE RESULTS
IR Tanger MAR-NR Borj Bou Arrérij ALG (0-3)
ES Sahel TUN-Bafia CMR (3-0)
Autoridade MOZ-Espoir Kinshasa DRC (1-3)
CS Sfaxien TUN-ES Sétif ALG (3-2)
GSU Club KEN-Ahly Benghai LBA (0-3)
ES Tunis TUN-Nemostars UGA (3-0)
Cement ETH-Port Douala CMR (0-3)
Prisons KEN-Beau Vallon SEY (3-0)
Ahly Tripoli LBA-Ahly EGY (1-3)